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Omega-3 Mechanism of Action

Potential mechanisms by which Omega-3 may reduce risk of cardiovascular disease:

  • Reduce susceptibility of the heart to ventricular rrhythmia
  • Antithrombogenic
  • Hypotriglyceridemic (fasting and postprandial)
  • Retard growth of atherosclerotic plaque
  • Reduce adhesion molecule expression
  • Reduce platelet-derived growth factor
  • Anti-inflammatory
  • Promote nitric oxide-induced endothelial relaxation
  • Mildly hypotensive

Depression and mood-related disorders are thought to be aided by:

  • Increasing membrane fluidity
  • Normalizing signal transduction
  • Reducing inflammation
  • Activating nuclear receptors

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